FL 1060: a new beta-lactam antibiotic with novel properties

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

FL 1060: a new beta-lactam antibiotic with novel properties.

The effect of FL 1060, a newly described beta-lactam antibiotic, on three strains of Escherichia coli was studied. The agent showed extraordinarily high activity as judged by conventional titrations, but inoculum size, osmolality of the medium, and length of the incubation period were all found to have a marked effect on the result. Continuous turbidimetric monitoring and microscopical observat...

متن کامل

Thienamycin: new beta-lactam antibiotic with potent broad-spectrum activity.

Thienamycin, a new beta-lactam antibiotic, exhibited potent, broad-spectrum activity in vitro against gram-negative bacilli and gram-positive cocci, including many isolates resistant to currently available antibiotics. All isolates were inhibited at concentrations less than or equal to 25 mug/ml, with the exception of 12% of isolates of Enterobacter spp. and 3% of isolates of Serratia marcescen...

متن کامل

zinc finger nuclease: a new approach to overcome beta-lactam antibiotic resistance

conclusions our findings revealed that the zfn technology could be employed to overcome ampicillin resistance by the targeted disruption of the ampicillin resistance gene, which leads to inactivation of β-lactam synthesis. therefore, zfn technology could be engaged to decrease the antibiotic resistance issue with the construction of a zfn archive against different args. to tackle the resistance...

متن کامل

pFJ269, a new plasmid isolated from a beta-lactam antibiotic producing streptomycete.

Streptomyces are Gram-positive, filamentous bacteria which have a complex life cycle that includes formation of substrate and aerial mycelia and spores. Streptomyces produce approximately 70% of all naturally occurring antibiotics, 2) and it is in the commercial production of antibiotics that this genus has been exploited. While the genetics and molecular biology of many Streptomyces are poorly...

متن کامل

A novel beta-lactam antibiotic activates tumor cell apoptotic program by inducing DNA damage.

Many of the anticancer drugs in current use are toxic and thus limited in their efficacy. It therefore becomes essential to develop novel chemotherapeutic agents with lower levels of toxicity. The beta-lactam antibiotics have been used for many years to treat bacterial infections with limited or no toxicity. Until now, it has never been shown that beta-lactams could kill tumor cells. Here, for ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1973

ISSN: 0021-9746

DOI: 10.1136/jcp.26.1.1